Abstract: To prevent people from using the processed turquoise and counterfeit turquoise in medicine, this paper focuses on identifying the raw materials of medicinal turquoise. A turquoise identification system was developed using hyper-spectral imaging technology. The sample standard spectral line was obtained while the applicability was analyzed by the present sample, based on the high-resolution spectral data of ore samples from 6 representative producing areas of natural turquoise in China. A new method was summarized by the differences in correlation coefficients in the range of 400 nm~1000 nm and 400 nm~600 nm of the fake turquoise on the market and an experimental prototype system to identify the true or false of turquoise was developed. Further research will provide technical support to select raw materials in mineral medicine, which will greatly promote the modernization of Tibetan medicine.