Abstract: In this mini-review, recent advances in the fiber optofluidic lasers and passive fiber optofluidic sensors are introduced. Fiber optofluidic laser can detect the biochemical changes using its laser output as a sensing signal. The cross-section of fiber can be used as a microcavity, providing optical feedback. The microcavity enhances the light-matter interaction, thus increasing the sensitivity. Furthermore, the geometry of optical fibers is uniform, easy to be mass produced with low cost, can be used to realize highly reproducible and disposable optofluidic laser. Passive fiber optofluidic sensors are also introduced based on the laser induced force and photo-thermal effects, which is flexible, easy to be integrated, multi-functional and reconfigurable.