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    • 摘要: 针对现有内窥光学相干层析成像(OCT)探头在视场、分辨率及尺寸等方面的局限性,提出一种新型大视场前向扫描内窥探头的设计方案。该探头采用由6片外径为1.4 mm的球面透镜组成的光学系统,结合压电陶瓷驱动光纤扫描技术,在1000~1100 nm波段下实现6.0 mm扫描视场、24 μm横向分辨率、20 μm轴向分辨率,机械外径仅为1.6 mm。搭建配套扫频光学相干层析系统,离体猪眼成像实验结果表明,该探头可清晰分辨虹膜、巩膜及视网膜结构,并能观测视网膜脱落现象。与渐变折射率透镜探头相比,其视场更大且伪影更少。研究证明该探头兼顾微型化、高分辨率和大视场优势,为眼科微创手术导航提供新方案。未来可通过进一步缩小外径、集成二维扫描功能提升临床应用潜力。

       

      Abstract: This study addresses the limitations of existing endoscopic optical coherence tomography (OCT) probes in field of view (FOV), resolution, and dimensions constraints by proposing a novel design for a large-FOV forward-scanning endoscopic probe. The probe employs an optical system comprising six spherical lenses with an outer diameter of 1.4 mm, integrated with piezoelectric ceramic-driven fiber scanning technology. Operating in the 1000-1100 nm wavelength range, it achieves a scanning FOV of 6.0 mm, a lateral resolution of 24 μm, and an axial resolution of 20 μm, while maintaining a compact mechanical outer diameter of merely 1.6 mm. A swept-source OCT system was developed to validate the probe’s performance through imaging experiments on ex vivo porcine eyes. Results demonstrate the probe’s capability to clearly distinguish iris, sclera, and retinal structures, as well as visualize retinal detachment phenomena. Comparative analyses with graded-index lens probes reveal superior FOV expansion and reduced imaging artifacts. The study confirms that this probe effectively integrates miniaturization, high-resolution imaging, and large-FOV advantages, providing a new solution for ophthalmic minimally invasive surgical navigation. Future research could focus on further reducing the outer diameter and integrating two-dimensional scanning functionality to enhance its clinical potential.